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ACE Inhibitor Efficacy (ACE inhibitors, drug side effects)

Nephrology 07.001

ACE Inhibitor Efficacy (ACE inhibitors, drug side effects)

HYPT

Signs/symptoms: Efficacy of statins and gemfibrozil in hyperlipidemia, efficacy of betablocker in heart failure, efficacy of ACE inhibitors
Complications: Hyperlipidemia, hypertension.
Early diagnosis/treatment: Yes

Material required:

Blood tubes: EDTA whole blood (do not freeze, do not centrifugate)
Mouth brush: No
Chromosomal localization: 17q23 OMIM number: 106180

Angiotensin I converting enzyme (insertions/deletions polymorphism)

ACE

Gene regions tested:

Gene regions:
Amino acid positions: insertion/deletion polymorphism
Nucleotide positions:
Test methods: Restriction Fragment Length

Prices:

Switzerland:

8820.00 8811.01 8819.01
  TP REVAL: 250 TP Value: 0.9 CHF 225.00
Other europe: EUR 160.00
Other regions: USD call

References:

Weekers L, Bouhanick B, Hadjadj S, Gallois Y, Roussel R, Pean F, Ankotche A, Chatellier G, Alhenc-Gelas F, Lefebvre PJ, Marre M. Modulation of the renal response to ACE inhibition by ACE insertion/deletion polymorphism during hyperglycemia in normotensive, normoalbuminuric type 1 diabetic patients. Diabetes. 2005;54:2961-2967.

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