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Coumarine Efficacy (CAP2C9, drug side effects)

Angiology 05.001

Coumarine Efficacy (CAP2C9, drug side effects)

PHGN
Signs/symptoms: Efficacy of coumarin derivatives
Complications: Thrombosis or bleeding.
Early diagnosis/treatment: Yes

Material required:
Blood tubes: EDTA whole blood (do not freeze, do not centrifugate)
Mouth brush: Yes
Chromosomal localization: 10q24 OMIM number: 601130

Cytochrome P450, subfamily 2C, polypeptide 9

CYP2CC9

Gene regions tested:
Gene regions:
Amino acid positions: C416T, A1061C
Nucleotide positions:
Test methods: Sequencing

Prices:

Switzerland:
8820.00 8811.01 8819.01
  TP REVAL: 350 TP Value: 0.9 CHF 315.00
Other europe: EUR 215.00
Other regions: USD call

References:
Taube J, Halsall D, Baglin T. Influence of cytochrome P-450 CYP2C9 polymorphisms on warfarin sensitivity and risk of over-anticoagulation in patients on long-term treatment. Blood. 2000;96:1816-1819.

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