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Atherosclerosis Association Marker (SELP)

Cardiology 04.006

Atherosclerosis Association Marker (SELP)

ATHSCL
Signs/symptoms: Myocardial infarction
Complications: Atherosclerosis, coronary heart disease
Early diagnosis/treatment: Yes

Material required:
Blood tubes: EDTA whole blood (do not freeze, do not centrifugate)
Mouth brush: Yes
Chromosomal localization: 1q23-q25 OMIM number: 173610

Selectin P (mutation V460L)

SELP

Gene regions tested:
Gene regions:
Amino acid positions: V460L
Nucleotide positions:
Test methods: Sequencing

Prices:

Switzerland:
8820.00 8811.01 8819.01
  TP REVAL: 250 TP Value: 0.9 CHF 225.00
Other europe: EUR 160.00
Other regions: USD call

References:
Herrmann, S.-M.; Ricard, S.; Nicaud, V.; Mallet, C.; Evans, A.; Ruidavets, J.-B.; Arveiler, D.; Luc, G.; Cambien, F. The P-selectin gene is highly polymorphic: reduced frequency of the pro715 allele carriers in patients with myocardial infarction. Hum. Molec. Genet. 7: 1277-1284, 1998.
Zee, R. Y. L.; Cook, N. R.; Cheng, S.; Reynolds, R.; Erlich, H. A.; Lindpaintner, K.; Ridker, P. M. Polymorphism in the P-selectin and interleukin-4 genes as determinants of stroke: a population-based, prospective genetic analysis. Hum. Molec. Genet. 13: 389-396, 2004.

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